Six TGA-approved medications are currently used for weight management in Australia. They range from weekly injections producing 15–21% body weight loss to daily tablets producing 3–10%. Here's how they all compare.
| Medication | Type | Avg. loss | Cost/mo | Duration | Status |
|---|---|---|---|---|---|
| Mounjaro | Injection | ~21% | $350–$500 | Long-term | Available |
| Wegovy | Injection | 15–17% | $400–$460 | Long-term | Available |
| Duromine | Tablet | 5–10% | ~$100 | 12 weeks max | Available |
| Contrave | Tablet | 5–10% | ~$300 | Long-term | Available |
| Xenical | Tablet | 3–5% | ~$80 | Long-term | OTC available |
| Ozempic | Injection | ~15% | $130–190 | Long-term | Diabetes only |
| Saxenda | Injection | ~8% | N/A | — | Discontinued |
Semaglutide 2.4mg. 15–17% avg weight loss. PBS pending. Best-studied option with CV benefits.
Full guide →Tirzepatide. ~21% avg weight loss. Dual mechanism. Most effective option available.
Full guide →Semaglutide 1mg. Restricted for weight loss since Oct 2024. PBS for diabetes.
Full guide →Phentermine. Short-term only (12 weeks). Cheapest option. Good as a kickstart.
Full guide →Naltrexone/bupropion. Best for emotional eating and cravings. Oral tablet.
Full guide →Orlistat. Fat blocker. Cheapest. Available OTC at 60mg. Modest results.
Full guide →The best medication depends on your individual circumstances:
The best medication depends on your individual circumstances. Consider these decision factors:
Still not sure? Use our interactive comparison tool →