Updated 2026-04-03
Compare weight loss medications
Every combination compared — effectiveness, cost, side effects, and suitability. Choose the comparison that matters to you.
Quick comparison
| Medication | Avg. loss | Cost/mo | Type | Duration | Best for |
|---|---|---|---|---|---|
| Mounjaro | ~21% | $350–500 | Injection | Long-term | Maximum weight loss |
| Wegovy | 15–17% | $400–460 | Injection | Long-term | Best-studied, CV benefits |
| Duromine | 5–10% | ~$100 | Tablet | 12 weeks | Budget, kickstart |
| Contrave | 5–10% | ~$300 | Tablet | Long-term | Emotional eating |
| Xenical | 3–5% | ~$80 | Tablet | Long-term | Cheapest, OTC |
Head-to-head comparisons
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Ozempic vs Wegovy
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Wegovy vs Mounjaro: which is better?
Not sure where to start?
If you're new to weight loss medication, start with these comparisons:
- First decision: Injections vs tablets — which format suits you?
- If choosing an injection: Wegovy vs Mounjaro — the two most effective options
- If choosing a tablet: Duromine vs Contrave — short-term vs long-term oral options
- If budget is key: Cheapest options ranked
Or use our interactive comparison tool to filter and sort all medications by what matters most to you.